cardiology research project ideas
Some examples of possible research topics for your Minor Internship, Major Internship or Literature Study:
- Diastolic Heart Failure: Our extensive collaborative research endeavour will achieve a better understanding of diastolic heart failure, improved diagnostic algorithms, and novel therapeutic inroads.
- Hypertrophic Cardiomyopathy: It is of the utmost clinical and societal importance to identify the cause of transition from mutation to cardiac remodelling and failure.
- Right Ventricular Failure in PAH: Our studies focus on the mechanisms and treatment of right ventricular failure and pulmonary arterial hypertension, and as such bridge the two main ICaR-VU themes.
- Cardiovascular Imaging: Advanced imaging is essential for non-invasive diagnosis of cardiovascular diseases and for monitoring response to therapy.
- Acute Coronary Syndrome and Repair: A unique feature is the use of porcine models combined with MRI imaging, which allows us to closely mimic the procedures encountered in the hospital.
- Aneurysm: Our translational studies have resulted in the implementation of a new surgical technique for our standard patient care.
- ReproductionandVascularFunction: Pregnancy provides a unique window of opportunity for exposing the hidden risks of vascular disease in women at the earliest stage possible.
- Diabetes Mellitus and Obesity: Only a multi-disciplinary approach can fully explore the most promising pathways to prevent, treat and cure diabetes and its cardiometabolic complications.
- Nutrition Research: Optimization of nutritional support during the first postnatal weeks may reduce occurrence of metabolic syndrome and associated cardiovascular disease.
- Chronic Kidney Disease: Cardiorenal interaction and related metabolic pathophysiological mechanisms are being studied in newly developed animal and cellular experimental models and multicenter intervention studies.
- Acute and Perioperative Care: Optimization of vital functions plays a central role during surgery or in the setting of intensive care requires. Clinical and experimental studies focus on haemostasis and tissue perfusion in distinct settings.
Top Cardiology Videos of 2017:
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Aortic valve disease—repair and surgery
Policy development is a forward looking exercise. In health research, medical needs identified by health data and expert opinion, are an important consideration. 27 Past research output helps to identify areas that may need more investment. Research funders also use input from society. 28 When assessing current priorities in cardiovascular research for the Dutch 28 and British 29 Heart Foundations we can see that research into heart failure and arrhythmias are common across their top priorities. Focus on healthy lifestyles is a top priority in the Dutch Heart Foundation as well as in the US vision and strategic agenda. 4 , 5 At the macro-level, the data presented here indicate that some of the main issues presented in these research agendas are actively pursued but others less so.
We have used the model also to prove the validity of an extremely simple model of cardiac electrograms . This simple model can help to gain insight in these signals.
Several cardiac arrhythmic syndromes have been attributed to mutations in the genes encoding cardiac ion channels. In many subjects, however, no mutations have been established yet. On the other hand, structural damage to the heart muscle (cardiomyopathy) has been observed in many of these subjects. The combination of structural and ionic abnormalities can disturb the propagation of the activating impulse, and can lead to arrhythmia. Research that I have done in collaboration with the Experimental Cardiology department of the University of Amsterdam has demonstrated that this can be the case in Brugada syndrome, a syndrome that is responsible for many sudden cardiac deaths in young, apparently healthy subjects.
Global longitudinal strain and wall motion score index measured early in NSTEMI patients predict final infarct size and may therefore be excellent parameters to identify patients with substantial MI who may benefit from urgent reperfusion therapy.
Cardiac troponin T levels in the population measured by a new highly sensitive assay is associated with LV hypertrophy and systolic dysfunction and independently associated with all-cause mortality.